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Young men at highest risk of schizophrenia linked with cannabis use disorder

NIH study highlights the need to proactively screen for, prevent, and treat cannabis use disorder especially among young people.

NIH

A study led by researchers at the Mental Health Services in the Capital Region of Denmark and the National Institute on Drug Abuse (NIDA) at the National Institutes of Health found that young men with cannabis (marijuana) use disorder have an increased risk of developing schizophrenia. Published in Psychological Medicine, the study analyzed detailed health records data over five decades, representing more than six million people in Denmark, to estimate the fraction of schizophrenia cases that could be attributed to cannabis use disorder. The research revealed a strong association between cannabis use disorder and schizophrenia among both men and women, with a notably stronger link among young men. Statistical models used in the study suggested that up to 30% of schizophrenia cases among men aged 21-30 might have been prevented by avoiding cannabis use disorder. Both cannabis use disorder and schizophrenia are serious, yet treatable, mental health conditions that can profoundly impact individuals’ lives. Cannabis use disorder involves an inability to stop using cannabis despite its negative consequences, while schizophrenia affects how a person thinks, feels, and behaves, often making them seem disconnected from reality. Effective treatments are available for both disorders.

Key Points:

  • Young men with cannabis use disorder are at a higher risk of developing schizophrenia.
  • The study analyzed over 50 years of data from more than 6 million people in Denmark.
  • Up to 30% of schizophrenia cases in men aged 21-30 could be prevented by avoiding cannabis use disorder.
  • Cannabis use disorder involves an inability to stop using cannabis despite negative consequences.
  • Schizophrenia affects thinking, feeling, and behavior, often causing a loss of touch with reality.
  • Effective treatments are available for both cannabis use disorder and schizophrenia.

The findings from this extensive study underscore the critical connection between cannabis use disorder and an increased risk of schizophrenia, particularly among young men. With up to 30% of schizophrenia cases in men aged 21-30 potentially preventable by avoiding cannabis use disorder, the importance of this information cannot be overstated. Both cannabis use disorder and schizophrenia are serious conditions that profoundly impact individuals’ lives, but effective treatments are available. Recognizing the risks and seeking help to quit using marijuana can lead to a healthier, more stable future. Quitting now can not only improve your mental health but also significantly reduce the risk of developing severe, life-altering conditions.

Reference: https://www.nih.gov/news-events/news-releases/young-men-highest-risk-schizophrenia-linked-cannabis-use-disorder

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